ea0037gp.20.09 | Pituitary – Hypopituitarism | ECE2015
Koulouri Olympia
, Moran Carla
, Powlson Andrew
, Antoun Nagui
, Donnelly Neil
, Mannion Richard
, Pickrd John
, Halsall David
, Chatterjee Krish
, Gurnell Mark
Background: Thyrotropinomas (TSHomas) are traditionally considered a rare, albeit important cause of thyrotoxicosis. Although early case series reported a predominance of invasive macroadenomas, emerging evidence suggests microadenomas are being increasingly diagnosed, and the clinical/biochemical phenotype appears to be more variable than previously suspected. We therefore performed detailed phenotyping of patients referred to our centre with a diagnosis of TSHoma over a 4-ye...